The present study examined the physiological effect of yogic package Dhanurasana, Gomukhasana, Kapalbhati, and Anulom-Viloma Pranayama in diabetes mellitus patients. The subjects were assigned by accidental sampling to two conditions namely, control n25 and experimental n25. The Subjects in experimental group were exposed to yogic package daily for half an hour for 40 days. Glucometer and Sinha’s Anxiety Test were used as the measure and Data collection was done individually in group and best attempts were made to avoid external distractions. The results of the study show that yogic package was found to reduce positively lower towards normal the fasting serum glucose level and post-prandial serum glucose level in patients of Diabetes Mellitus.