Health psychology which is directly and practically concerned with various aspects of one’s life, is an emerging field not only in India but also throughout the world. It is perhaps the dedicated efforts of health psychologists that the psychosocial influences have gained due attention that push and pull one in healthy or unhealthy state of affairs across time. While studying the key role of psychological factors in the prevention and treatment of diseases, it has been reiterated to examine the role of personality in relation to health. Working on these lines, the present study was conducted to examine the correlation between personality traits and general health. Three hundred educated adults were administered the 16 Personality Factors Test and General Health Questionnaire. Pearson product-moment correlations were computed to draw a personality profile wherein major personality factors associated with better and poor mental health were sorted out. The findings have crucial implications for providing better care and health services according to personality of an individual.